Desarrollo de una estrategia eficaz de difusión de vacunas orales contra la peste porcina clásica para jabalíes en la prefectura de Gifu, Japón
Publicamos un nuevo artículo en la revista Transboundary and Emerging Diseases.
Resumen: In September 2018, classical swine fever (CSF) reemerged in Japan after more than a quarter of a century. After the first notification on a pig farm, wild boars positive for CSF were found continuously in the surrounding area. Gifu was the first prefecture in Japan to disseminate oral vaccines to wild boars in March 2019, with vaccines spread to approximately 14,000 sites between 2019 and 2020. While these diligent measures seemed to have shown some effectiveness, several vaccine spray sites remained without wild boar emergence. Based on the vaccine dissemination records from these periods, this study conducted a statistical analysis to propose more effective vaccine dissemination sites. First, a generalized linear mixed model was used to identify factors correlated with wild boar emergence. Then, two spatial interpolation methods, inverse distance weighted (IDW) and Kriging, were adopted to create a probability map of wild boar emergence for the entire Gifu Prefecture. The analysis showed a positive correlation between wild boar emergence and the appearance of raccoons, raccoon dogs, and crows as well as road density and wild boar distribution index. In particular, raccoon (OR: 1.83, 95%CI: 1.25–2.68, < 0.001), raccoon dog (OR: 1.81, 95%CI: 1.25–2.66, < 0.001), and medium level road density (OR: 1.56, 95%CI: 1.04–2.39, = 0.04) were strongly correlated with wild boar emergence. The spatial interpolation approach resulted in better prediction accuracy for the Kriging method than for IDW by the root mean square error, but both approaches identified a high wild boar appearance probability area in southeastern Gifu and a low appearance probability area in central Gifu. Here we have demonstrated a tool to effectively disperse oral vaccine to wildlife.
Ito S, Bosch J, Aguilar-Vega C, Isoda N, Martinez-Aviles M and Sanchez-Vizcaino JM.
Spatio-Temporal Epidemiology of the Spread of African Swine Fever in Wild Boar and the Role of Environmental Factors in South Korea
Publicamos un nuevo artículo en la revista Viruses.
Resumen: Since the first confirmation of African swine fever (ASF) in domestic pig farms in South Korea in September 2019, ASF continues to expand and most notifications have been reported in wild boar populations. In this study, we first performed a spatio-temporal cluster analysis to understand ASF spread in wild boar. Secondly, generalized linear logistic regression (GLLR) model analysis was performed to identify environmental factors contributing to cluster formation. In the meantime, the basic reproduction number (R0) for each cluster was estimated to understand the growth of the epidemic. The cluster analysis resulted in the detection of 17 spatio-temporal clusters. The GLLR model analysis identified factors influencing cluster formation and indicated the possibility of estimating ASF epidemic areas based on environmental conditions. In a scenario only considering direct transmission among wild boar, R0 ranged from 1.01 to 1.5 with an average of 1.10, while, in another scenario including indirect transmission via an infected carcass, R0 ranged from 1.03 to 4.38 with an average of 1.56. We identified factors influencing ASF expansion based on spatio-temporal clusters. The results obtained would be useful for selecting priority areas for ASF control and would greatly assist in identifying efficient vaccination areas in the future.
Ito S., Bosch J., Jeong H., Aguilar-Vega C., Park J., Martinez-Aviles M. y Sanchez-Vizcaino JM.
Vacdiva Policy Event
El proyecto EU H2020 VACDIVA organiza un Policy Event el próximo 29 de noviembre en Madrid.
Repasaremos la situación de riesgo global y los avances en el desarrollo de una vacuna segura, eficaz y DIVA.
Lección inaugural en la UCAM
Entrevista para The Guardian
Los científicos se apresuran a crear una vacuna para el mayor brote de enfermedad animal del mundo.
Artículo en el periódico The Guardian en la que entrevistan al Profesor Sánchez-Vizcaíno.
Feria Internacional Ganadera de Zafra
El pasado viernes 30 de septiembre el Profesor Sánchez-Vizcaíno participó en Feria Ganadera de Zafra 2022: https://fig.zafra.es/