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Pertenecemos al Centro de Investigación VISAVET de la Universidad Complutense de Madrid (UCM). Trabajamos en investigación y en docencia de enfermedades infecciosas animales.

 
  • Vigiasan: Proyecto de Innovación Empleo de Tecnologías para evaluar el estado de salud, bienestar y productividad en ganado

  • VACDIVA quiere resolver el problema de la Peste Porcina Africana (PPA) en Europa y en los países afectados, desarrollando vacunas seguras y efectivas para cerdos domésticos y jabalíes, tests de diagnóstico y herramientas para estrategias de control y erradicación en Europa
  • Proyecto de Innovación "Empleo de Tecnologías para evaluar el estado de salud, bienestar y productividad en ganado"
  • Somos Laboratorio de Referencia de la Organización Mundial de la Sanidad Animal (OIE) en Peste Porcina Africana (PPA) y Peste Equina Africana PEA.
  • Realizamos el diagnóstico de los principales virus que afectan a las abejas, siendo pioneros en el desarrollo y puesta a punto de nuevas técnicas para su estudio.
  • La investigación epidemiologica de la Peste Porcina Clásica y Africana (PPC y PPA) son dos de nuestras prioridades.

Destacados

Peste Porcina Africana Vídeos PPA Mapa Peste Porcina Africana
 
Sanidad Marina VACDIVA ASF NIFNAF

Riesgo de introducción de la Peste Porcina Africana en España por importación de cerdos

Nuevo artículo de investigación publicado en la revista Pathogens "Quantitative Risk Assessment of African Swine Fever Introduction into Spain by Legal Import of Live Pigs"

African swine fever (ASF) is a devastating infectious disease of pigs that is threatening the global swine industry at present. The current spread of ASF in Europe and its recent incursion into Germany pose a serious risk to Spain, one of the world’s leading pig producers. A quantitative stochastic risk assessment model was developed to estimate the probability of ASF introduction into Spain via the legal import of live pigs. The results suggest a low annual probability of ASF introduction into Spain (1.07 × 10−4), the highest risk being concentrated in Central European countries (Germany, the Netherlands, Belgium, and Luxembourg) during the months of April and February. The methods and results presented herein could contribute to improving prevention and control strategies and, ultimately, would help reduce the risk of ASF introduction into Spain.

Muñoz-Pérez C, Bosch J, Ito S, Martínez-Avilés M y Sánchez-Vizcaíno JM.

Noticia en los medios
Diario Veterinario: Alemania, país con más riesgo de introducir peste porcina africana en España

Nuevo artículo publicado en Frontiers in Immunology

Safety of African Swine Fever Vaccine Candidate Lv17/WB/Rie1 in Wild Boar: Overdose and Repeated Doses.

Resumen: African swine fever (ASF) is a highly lethal infectious disease that affects domestic pigs and wild boar. Outbreaks of ASF have grown considerably in the last decade causing important economic consequences for the swine industry. Its control is hampered by the lack of an effective treatment or vaccine. In Europe, the wild boar is a key wild reservoir for ASF. The results of the oral vaccination trial of wild boar with Lv17/WB/Rie1 are hope for this problem. However, this vaccine candidate has certain safety concerns, since it is a naturally attenuated vaccine. Therefore, the current study aims to evaluate the safety of this vaccine candidate in terms of overdose (high dose) and repeated doses (revaccination) in wild boar. Low-dose orally vaccinated animals developed only a slight transient fever after vaccination and revaccination. This was also the case for most of the high-dose vaccinated wild boar, except for one of them which succumbed after revaccination. Although this fatality was related to hierarchical fights between animals, we consider that further studies are required for clarification. Considering these new results and the current epidemiological situation of ASF in wild boar, this vaccine prototype is a promising tool for the control of the disease in these wild populations, although further studies are needed.

Barasona JA, Cadenas-Fernández E, Kosowska A, Barroso-Arévalo S, Rivera B, Sánchez R, Porras N, Gallardo C y Sánchez-Vizcaíno JM.

 Acceso abierto al artículo

Premio Isabel Mínguez Tudela a la Innovación en Sanidad Animal

José Manuel Sánchez-Vizcaíno, catedrático de Sanidad Animal en la Universidad Complutense de Madrid (UCM) e investigador del Centro de Vigilancia Sanitaria Veterinaria (VISAVET), y Marisa Arias, directora del Centro de Investigación en Sanidad Animal (CISA-INIA), han sido galardonados con el VII Premio Isabel Mínguez Tudela a la Innovación en Sanidad Animal durante la XII Conferencia Anual de la Fundación Vet+i, celebrada este jueves 25 de noviembre de 2021.

Noticia completa en la revista Animal's Health

Defensa de tesis de Daniel García Párraga

Daniel García Párraga defendió su Tesis Doctoral titulada "Avances en el conocimiento de la fisiopatología del buceo en tortugas marinas: El descubrimiento de la enfermedad descompresiva" dirigido por José Manuel Sánchez-Vizcaíno y Antonio Jesús Fernández Rodríguez.

La defensa tuvo lugar el miércoles 17 de noviembre de 2021 en el Centro de Vigilancia Sanitaria Veterinaria de la Universidad Complutense. El trabajo obtuvo la máxima calificación de sobresaliente cum laude

¡Felicidades Daniel! El equipo SUAT te da la más sincera enhorabuena 

Continuar leyendo

Nuevo artículo de acceso abierto en la revista Viruses

Publicamos un nuevo artículo titulado: Systematic Determination of Herpesvirus in Free-Ranging Cetaceans Stranded in the Western Mediterranean: Tissue Tropism and Associated Lesions

Resumen: The monitoring of herpesvirus infection provides useful information when assessing marine mammals’ health. This paper shows the prevalence of herpesvirus infection (80.85%) in 47 cetaceans stranded on the coast of the Valencian Community, Spain. Of the 966 tissues evaluated, 121 tested positive when employing nested-PCR (12.53%). The largest proportion of herpesvirus-positive tissue samples was in the reproductive system, nervous system, and tegument. Herpesvirus was more prevalent in females, juveniles, and calves. More than half the DNA PCR positive tissues contained herpesvirus RNA, indicating the presence of actively replicating virus. This RNA was most frequently found in neonates. Fourteen unique sequences were identified. Most amplified sequences belonged to the Gammaherpesvirinae subfamily, but a greater variation was found in Alphaherpesvirinae sequences. This is the first report of systematic herpesvirus DNA and RNA determination in free-ranging cetaceans. Nine (19.14%) were infected with cetacean morbillivirus and all of them (100%) were coinfected with herpesvirus. Lesions similar to those caused by herpesvirus in other species were observed, mainly in the skin, upper digestive tract, genitalia, and central nervous system. Other lesions were also attributable to concomitant etiologies or were nonspecific. It is necessary to investigate the possible role of herpesvirus infection in those cases.

Vargas-Castro I, Melero M, Crespo-Picazo JL, Jiménez MdlÁ, Sierra E, Rubio-Guerri C, Arbelo M, Fernández A, García-Párraga D, y Sánchez-Vizcaíno JM. 

 Acceso al artículo

Un nuevo método para muestrear el genoma del virus de la Peste Porcina Africana y su inactivación en muestras ambientales

Nuevo artículo publicado en la revista Scientific Records de Nature research.

Resumen: African swine fever (ASF) is currently the most dangerous disease for the global pig industry, causing huge economic losses, due to the lack of effective vaccine or treatment. Only the early detection of ASF virus (ASFV) and proper biosecurity measures are effective to reduce the viral expansion. One of the most widely recognized risks as regards the introduction ASFV into a country is infected animals and contaminated livestock vehicles. In order to improve ASF surveillance, we have assessed the capacity for the detection and inactivation of ASFV genome by using Dry-Sponges (3 M) pre-hydrated with a new surfactant liquid. We sampled different surfaces in ASFV-contaminated facilities, including animal skins, and the results were compared to those obtained using a traditional sampling method. The surfactant liquid successfully inactivated the virus, while ASFV DNA was well preserved for the detection. This is an effective method to systematically recover ASFV DNA from different surfaces and skin, which has a key applied relevance in surveillance of vehicles transporting live animals and greatly improves animal welfare. This method provides an important basis for the detection of ASFV genome that can be assessed without the biosafety requirements of a BSL-3 laboratory at least in ASF-affected countries, which may substantially speed up the early detection of the pathogen.

Kosowska A, Barasona JA, Barroso-Arévalo S, Rivera B, Domínguez L, Sánchez-Vizcaíno JM.

 Acceso abierto al artículo