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Pertenecemos al Centro de Investigación VISAVET de la Universidad Complutense de Madrid (UCM). Trabajamos en investigación y en docencia de enfermedades infecciosas animales.

 

  • Vigiasan: Proyecto de Innovación Empleo de Tecnologías para evaluar el estado de salud, bienestar y productividad en ganado

  • VACDIVA quiere resolver el problema de la Peste Porcina Africana (PPA) en Europa y en los países afectados, desarrollando vacunas seguras y efectivas para cerdos domésticos y jabalíes, tests de diagnóstico y herramientas para estrategias de control y erradicación en Europa
  • Proyecto de Innovación "Empleo de Tecnologías para evaluar el estado de salud, bienestar y productividad en ganado"
  • Somos Laboratorio de Referencia de la Organización Mundial de la Sanidad Animal (OIE) en Peste Porcina Africana (PPA) y Peste Equina Africana PEA.
  • Realizamos el diagnóstico de los principales virus que afectan a las abejas, siendo pioneros en el desarrollo y puesta a punto de nuevas técnicas para su estudio.
  • La investigación epidemiologica de la Peste Porcina Clásica y Africana (PPC y PPA) son dos de nuestras prioridades.

Destacados

Peste Porcina Africana Vídeos PPA Mapa Peste Porcina Africana
 
Sanidad Marina VACDIVA ASF NIFNAF

Detectada en España la variante B.1.1.7 de SARS-CoV-2 en un perro asintomático

Artículo titulado "First Detection of SARS-CoV-2 B.1.1.7 Variant of Concern in an Asymptomatic Dog in Spain".

 Acceso abierto al artículo

Resumen: Natural SARS-CoV-2 infection in pets has been widely documented during the last year. Although the majority of reports suggested that dogs’ susceptibility to the infection is low, little is known about viral pathogenicity and transmissibility in the case of variants of concern, such as B.1.1.7 in this species. Here, as part of a large-scale study on SARS-CoV-2 prevalence in pets in Spain, we have detected the B.1.1.7 variant of concern (VOC) in a dog whose owners were infected with SARS-CoV-2. The animal did not present any symptoms, but viral loads were high in the nasal and rectal swabs. In addition, viral isolation was possible from both swabs, demonstrating that the dog was shedding infectious virus. Seroconversion occurred 23 days after the first sampling. This study documents the first detection of B.1.1.7 VOC in a dog in Spain and emphasizes the importance of performing active surveillance and genomic investigation on infected animals.

Barroso-Arévalo S., Rivera B., Domínguez L. y Sánchez-Vizcaíno JM.

¿Medio ambiente, vector u hospedador? Uso del "machine learning" para desenredar los mecanismos que provocan los brotes asociados a arbovirus

Publicamos este nuevo trabajo en la revista Ecological Applications de la prestigiosa Ecological Society of America.

 Acceso al artículo

Resumen: Climatic, landscape and host features are critical components in shaping outbreaks of vector-borne diseases. However, the relationship between the outbreaks of vector-borne pathogens and their environmental drivers is typically complicated, nonlinear and may vary by taxonomic units below the species level (e.g., strain or serotype).

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Artículo de acceso abierto en Parásitos y Vectores

Publicamos un nuevo artículo titulado "A study of the composition of the Obsoletus complex and genetic diversity of Culicoides obsoletus populations in Spain"

Resumen: 

Background: The Culicoides obsoletus species complex (henceforth 'Obsoletus complex') is implicated in the transmission of several arboviruses that can cause severe disease in livestock, such as bluetongue, African horse sickness, epizootic hemorrhagic disease and Schmallenberg disease. Thus, this study aimed to increase our knowledge of the composition and genetic diversity of the Obsoletus complex by partial sequencing of the cytochrome c oxidase I (cox1) gene in poorly studied areas of Spain.

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La vacuna contra la Peste Porcina Africana: convertir un sueño en realidad

Nuevo artículo de revisión sobre la Peste Porcina Africana.

 Acceso a la review

Resumen: African swine fever (ASF) is currently threatening the swine industry at a global level. The disease originated in Africa has spread to Europe, Asia and Oceania, since 2007, reaching a pandemic dimension. Currently, the spread of ASF is unstoppable and that the development of a safe and effective vaccine is urgently required. The objective of this paper is to review the vaccine candidates tested during the 20th and 21st centuries, to identify the strengths and weaknesses of these studies and to highlight what we should learn. Several strategies have been explored to date, some of which have shown positive and negative results. Inactivated preparations and subunit vaccines are not a viable option.

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Artículo de investigación publicado en Pathogens

The Role of Interleukine-10 and Interferon-γ as Potential Markers of the Evolution of African Swine Fever Virus Infection in Wild Boar

The Role of Interleukine-10 and Interferon-γ as Potential Markers of the Evolution of African Swine Fever Virus Infection in Wild Boar Acceso abierto al artículo

Resumen: African swine fever virus (ASFv) is one of the most challenging pathogens to affect both domestic and wild pigs. The disease has now spread to Europe and Asia, causing great damage to the pig industry. Although no commercial vaccine with which to control the disease is, as yet, available, some potential vaccine candidates have shown good results in terms of protection. However, little is known about the host immune mechanisms underlying that protection, especially in wild boar, which is the main reservoir of the disease in Europe. Here, we study the role played by two cytokines (IL-10 and IFN-γ) in wild boar orally inoculated with the attenuated vaccine candidate Lv17/WB/Rie1 and challenged with a virulent ASFv genotype II isolate.

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