Artículo de acceso abierto en Parásitos y Vectores
Publicamos un nuevo artículo titulado "A study of the composition of the Obsoletus complex and genetic diversity of Culicoides obsoletus populations in Spain"
Background: The Culicoides obsoletus species complex (henceforth 'Obsoletus complex') is implicated in the transmission of several arboviruses that can cause severe disease in livestock, such as bluetongue, African horse sickness, epizootic hemorrhagic disease and Schmallenberg disease. Thus, this study aimed to increase our knowledge of the composition and genetic diversity of the Obsoletus complex by partial sequencing of the cytochrome c oxidase I (cox1) gene in poorly studied areas of Spain.
Artículo dedicado al proyecto VACDIVA
La revista digital Open Access Government ha publicado este artículo sobre el proyecto.
La vacuna contra la Peste Porcina Africana: convertir un sueño en realidad
Nuevo artículo de revisión sobre la Peste Porcina Africana.
Resumen: African swine fever (ASF) is currently threatening the swine industry at a global level. The disease originated in Africa has spread to Europe, Asia and Oceania, since 2007, reaching a pandemic dimension. Currently, the spread of ASF is unstoppable and that the development of a safe and effective vaccine is urgently required. The objective of this paper is to review the vaccine candidates tested during the 20th and 21st centuries, to identify the strengths and weaknesses of these studies and to highlight what we should learn. Several strategies have been explored to date, some of which have shown positive and negative results. Inactivated preparations and subunit vaccines are not a viable option.
Artículo de investigación publicado en Pathogens
The Role of Interleukine-10 and Interferon-γ as Potential Markers of the Evolution of African Swine Fever Virus Infection in Wild Boar
Resumen: African swine fever virus (ASFv) is one of the most challenging pathogens to affect both domestic and wild pigs. The disease has now spread to Europe and Asia, causing great damage to the pig industry. Although no commercial vaccine with which to control the disease is, as yet, available, some potential vaccine candidates have shown good results in terms of protection. However, little is known about the host immune mechanisms underlying that protection, especially in wild boar, which is the main reservoir of the disease in Europe. Here, we study the role played by two cytokines (IL-10 and IFN-γ) in wild boar orally inoculated with the attenuated vaccine candidate Lv17/WB/Rie1 and challenged with a virulent ASFv genotype II isolate.
Natural SARS-CoV-2 Infection in Kept Ferrets, Spain
Publicamos este artículo en la revista del Center for Disease Control and Prevention (CDC).
Resumen: We found SARS-CoV-2 RNA in 6 of 71 ferrets (8.4%) and isolated the virus from one rectal swab. Natural SARS-CoV-2 infection does occur in kept ferrets, at least under circumstances of high viral circulation in the human population. However, small ferret collections are probably unable to maintain prolonged virus circulation.
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Un curso sobre cómo prevenir futuras pandemias desde el enfoque ‘One Health’
Entre los días 7 y 9 de julio tendrá lugar el curso 'Epidemias, zoonosis y pandemias. Una visión holística 'One Health'' de la UCM dirigido por los catedráticos Lucas Domínguez y José Manuel Sánchez-Vizcaíno